HIV persistence in the CNS: the final frontier for a cure?
| Author List |
|---|
| Sharon R Lewin |
| John W Mellors |
Abstract
Understanding how often, where, and by which mechanisms HIV persists in the central nervous system (CNS) in individuals on antiretroviral therapy (ART) is critical for preventing and managing CNS-related HIV complications and for designing strategies to achieve a cure of HIV infection. In this issue of the Journal of Virus Eradication, Joseph et al. [1] report on a ground breaking meeting convened by the National Institutes of Mental Health on ‘Cerebrospinal fluid (CSF) HIV-1 Escape’ with the goals of elucidating key knowledge gaps about this newly recognised entity, establishing a research agenda and assembling a ‘Global HIV-1 CSF Escape Consortium’ to fill these gaps.Understanding how often, where, and by which mechanisms HIV persists in the central nervous system (CNS) in individuals on antiretroviral therapy (ART) is critical for preventing and managing CNS-related HIV complications and for designing strategies to achieve a cure of HIV infection. In this issue of the Journal of Virus Eradication, Joseph et al. [1] report on a ground breaking meeting convened by the National Institutes of Mental Health on ‘Cerebrospinal fluid (CSF) HIV-1 Escape’ with the goals of elucidating key knowledge gaps about this newly recognised entity, establishing a research agenda and assembling a ‘Global HIV-1 CSF Escape Consortium’ to fill these gaps.
Article Category
HIV cure research
Article Type
Conference report
Posted Date
06-10-2016
| File Name |
|---|
| 1475735023jve-2-242.pdf |